Applied Biological Chemistry
- Volume 35 Issue 6
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- Pages.495-500
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- 1992
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- 2468-0834(pISSN)
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- 2468-0842(eISSN)
Production of 6-hydroxynicotinic acid by nicotinic acid-assimilating Pseudomonas sp.
Pseudomonas sp.에 의한 nicotinic acid로부터 6-hydroxynicotinic acid의 생산
- Hong, Jeong-Jin (Department of Agricultural Chemistry, Korea University) ;
- Hwang, Ki-Chul (Department of Agricultural Chemistry, Korea University) ;
- Bang, Won-Gi (Department of Agricultural Chemistry, Korea University)
- Published : 1992.12.30
Abstract
For the production of 6-hydroxynicotinic acid from nicotinic acid, bacteria capable of assimilating nicotinic acid as a sole carbon, nitrogen and energy source were isolated from soils. Among them, SH-007, newly isolated strain having the best acitivity of nicotinic acid hydroxylase was selected and identified as Pseudomonas sp. The specific acitivity of nicotinic acid hydroxylase of Pseudomonas sp. was highest when the strain was cultured at
미생물을 이용하여 nicotinic acid로부터 6-hydroxynicotinic acid를 생산하기 위하여 토양으로부터 nicotinic acid를 탄소원, 질소원 및 에너지원으로 이용하는 균주를 70종 분리 하였으며, 이들 균주로부터 nicotinic acid hydroxylase의 비활성이 가장 높은 균주인 SH-007를 선별하였고, Pseudomonas sp.로 동정되었다. Pseudomonas sp.의 SH-007의 nicotinic acid hydroxylase의 비활성은 배지 중 2 g/l nicotinic acid, 1 g/l(