Hydrogels for Drug Delivery System:-Colon-Specific Delivery-

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  • Park, Ki-Dong (Polymer Chemistry Lab., Korea Institute of Science and Technology) ;
  • Jeong, Seo-Young (Polymer Chemistry Lab., Korea Institute of Science and Technology) ;
  • Kim, Young-Ha (Polymer Chemistry Lab., Korea Institute of Science and Technology)
  • 박기동 (한국과학기술연구원, 고분자설계연구실) ;
  • 정서영 (한국과학기술연구원, 고분자설계연구실) ;
  • 김영하 (한국과학기술연구원, 고분자설계연구실)
  • Published : 1992.12.20

Abstract

A major problem with the peptide-based drugs is that these drugs must generally be administered by injection. Therefore, there is considerable research interest in alternative routes of delivery, such as buccal, nasal, gastrointestinal route and etc. Site-specific drug delivery to the colon, as an alternative to parenteral drug delivery, is of interest for the delivery of peptide-based drugs as well as the delivery of low molecular weight drugs for the treatment of colonic disease, This review describes some considerations of colon-specific drug delivery using hydrogels.

Keywords