Journal of Pharmaceutical Investigation
- Volume 22 Issue 4
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- Pages.251-266
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- 1992
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Hydrogels for Drug Delivery System:-Colon-Specific Delivery-
히드로겔을 이용한 약물수송시스템
- Park, Ki-Dong (Polymer Chemistry Lab., Korea Institute of Science and Technology) ;
- Jeong, Seo-Young (Polymer Chemistry Lab., Korea Institute of Science and Technology) ;
- Kim, Young-Ha (Polymer Chemistry Lab., Korea Institute of Science and Technology)
- Published : 1992.12.20
Abstract
A major problem with the peptide-based drugs is that these drugs must generally be administered by injection. Therefore, there is considerable research interest in alternative routes of delivery, such as buccal, nasal, gastrointestinal route and etc. Site-specific drug delivery to the colon, as an alternative to parenteral drug delivery, is of interest for the delivery of peptide-based drugs as well as the delivery of low molecular weight drugs for the treatment of colonic disease, This review describes some considerations of colon-specific drug delivery using hydrogels.