Studies on Uterus Contraction of the Components of Undaria pinnatifida

미역의 자궁수축에 관한 연구

  • 허근 (영남대학교 약학대학 약품개발연구소) ;
  • 송재웅 (영남대학교 약학대학 약품개발연구소) ;
  • 최종원 (경성대학교 약학대학)
  • Published : 1992.09.30

Abstract

Undaria pinnatifida (UP) has long been ingested by woman who was delivered of a child. The present study was investigated to find out the contractive compound from UP and the contractive mechanism. The active extract, MeOH extract was partitioned with $CHCl_3$ and water. Whereas potassium iodide and alginic acid do not affected the uterus contraction, $CHCl_3$ extract significantly increased uterus contraction in vitro and in situ studies. The contraction by $CHCl_3$ extract was not blocked by atropine, prazosin and propranolol. Blood estrogen level was not changed by $CHCl_3$ extract.

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