약학회지 (YAKHAK HOEJI)
- 제36권6호
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- Pages.563-569
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
생체시료로부터 미량 이부푸로펜의 고상추출에 사용될 흡착제들의 특성
Characterization of Adsorbents for the Solid-Phase Extraction of Trace Ibuprofen from Biological Samples
- Kim, Kyoung-Rae (College of Pharmacy, Sung Kyun Kwan University) ;
- Shim, Weon-Hee (College of Pharmacy, Sung Kyun Kwan University)
- 발행 : 1992.12.29
초록
The sorption and desorption properties of four different solid adsorbents were evaluated for the trace enrichment of ibuprofen from biological samples. Chromosorb 107 gave the highest dynamic adsorption coefficient. Among the organic solvents examined, acetone gave the highest desorption coefficient. Using the Chromosorb 107 column, the optimum elution volume of the eluting solvent was evaluated from the breakthrough curve of ibuprofen. The usefulness of Chromosorb 107 as the solid adsorbent and acetone as the eluting solvent was examined for the solid-phase extraction of ibuprofen from serum in the concentration range of