YAKHAK HOEJI (약학회지)
- Volume 36 Issue 6
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- Pages.548-555
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Biological Active Components of Fruits of Poncirus trifoliata
지실의 생리활성성분
- Youn, Whang-Geum (College of Pharmacy, Kyung Hee University) ;
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Kim, Dong-Hyun
(College of Pharmacy, Kyung Hee University) ;
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Kim, Nam-Jae
(East-West Medical Research Institute, Kyung Hee University) ;
- Hong, Nam-Doo (East-West Medical Research Institute, Kyung Hee University)
- Published : 1992.12.29
Abstract
The biological activities of fruits of Poncirus trifoliata have been studied. 70% Ethanol extract of Ponciri Fructus was fractionated with ether, ethyl acetate and n-butanol by turns. The ether fraction showed antibacterial activity on Staphylococcus aureus and inhibited the contractability of the isolated mice ileum. The ethyl acetate and n-butanol fractions showed the anti-edematous effect on the carrageenin-induced edema of rat hindpaw. From the n-butanol fraction, one of the flavonoid glycoside was isolated and identified as poncirin. Ponciri Fructus contained about 6% poncirin which was 5,7-dihydroxy-4´-methoxy flavanone rhamnoglucoside and poncirin showed antiinflammatory activities. Poncirin was considered as the major effective component of Ponciri Fructus.