약학회지 (YAKHAK HOEJI)
- 제36권5호
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- Pages.506-511
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
고속액체크로마토그라피에 의한 프로스타글란딘류의 고감도 형광 분석법
A Sensitive Fluorescent Detection Method for Prostaglandins by High Performance Liquid Chromatography
- Lee, Yong-Moon (College of Pharmacy, Chungbuk National University) ;
- Moon, Dong-Cheul (College of Pharmacy, Chungbuk National University)
- 발행 : 1992.10.29
초록
The Prostaglandins were derivatized rapidly with monodansyl cadaverine as a fluorophore in mild conditions. The carboxylic moiety of prostaglandins was activated with diethyl phosphorocyanidate and successively coupled with fluorophore in dimethylformamide at room temperature. The labeling yield was reached about 95% at 15 min using arachidic acid
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