YAKHAK HOEJI (약학회지)
- Volume 36 Issue 5
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- Pages.427-432
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Effects of Olfactory Bulbectomy on Catalepsy Induced by Haloperidol in Rats
흰쥐에서 할로페리돌에 의해서 유발된 강경증에 미치는 후구 적출의 영향
- Chun, Seoung-Ho (College of Pharmacy, Chungnam National University) ;
- Kim, Seon-Jang (College of Pharmacy, Chungnam National University) ;
- Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
- Lee, Soon-Chul (College of Pharmacy, Chungnam National University)
- Published : 1992.10.29
Abstract
We attempted to clarify the effect of bilateral olfactory bulbectomy on catalepsy induced by haloperidol in rats. The incidence of catalepsy induced by haloperidol remarkably increased after lesion of olfactory bulb, which was significantly inhibited by L-5-hydroxytryptophan, L-DOPA, and ginseng's total saponin but reserpine and