약학회지 (YAKHAK HOEJI)
- 제36권3호
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- Pages.191-198
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
혈액중 지페프롤의 가스크로마토그래피에 의한 분석
Gas Chromatographic Analysis of Zipeprol in Blood
- Yoo, Young-Chan (National Institute of Scientific Investigation) ;
- Chung, Hee-Sun (National Institute of Scientific Investigation) ;
- Kim, Eun-Mi (National Institute of Scientific Investigation)
- 발행 : 1992.06.29
초록
The abuse of zipeprol, an antitussive agent, is prevalent among young people. Ten fatal cases of zipeprol concentration in blood after its abuse had caused death are disscussed. GC equipped with TSD was used to quantify the drug in postmortem blood and GC/MS to identify the metabolites in urine after preliminary test. The calibration curve of zipeprol was linear (r = 0.998) and the recoveries of zipeprol 5, 10 and