The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
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Neuroleptic Malignant Syndrome after Epidural Administration of Droperidol

경막외 Droperidol 투여로 발생한 Neuroleptic Malignant Syndrome - 1예 보고 -

  • Ahn, Myung-Ja (Department of Anesthesiology, Catholic University Medical College) ;
  • Suh, Jae-Hyun (Department of Anesthesiology, Catholic University Medical College) ;
  • Kim, Sung-Nyeun (Department of Anesthesiology, Catholic University Medical College)
  • 안명자 (가톨릭대학 의학부 마취과학교실) ;
  • 서재현 (가톨릭대학 의학부 마취과학교실) ;
  • 김성년 (가톨릭대학 의학부 마취과학교실)
  • Published : 1991.06.08
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Abstract

The neuroleptic malignant syndrome (NMS) is an uncommon but dangerous complication of treatment with neuroleptic drugs. This syndrome is characterized by autonomic dysfunction, extrapyramidal dysfunction, and hyperthermia. NMS seems more frequent with parenteral neuroleptic use. We report a patient in whom suspicious NMS was developed in the ward after epidural administration of 2.5mg of droperidol with morphine for postoperative pain control. Extrapyramidal symptoms and autonomic dysfunction were treated with diazepam, but temperature was spontaneously decreased after 16 hours and 40 minute after receiving epidural droperidol.

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