Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
- Volume 7 Issue 2
- /
- Pages.114-119
- /
- 1991
- /
- 1229-5183(pISSN)
- /
- 2586-2553(eISSN)
A Case of Malignant Oncocytoma of the Parotid Gland
이하선에 발생한 악성 타액선 호산성 과립세포종 1례
- Park Yong-Jin (Department of Otolaryngology, Catholic University Medical College) ;
- Suh Young-Pyo (Department of Otolaryngology, Catholic University Medical College) ;
-
Kim Min-Sik
(Department of Otolaryngology, Catholic University Medical College)
;
- Cho Seung-Ho (Department of Otolaryngology, Catholic University Medical College) ;
- Suh Byung-Do (Department of Otolaryngology, Catholic University Medical College)
- 박용진 (가톨릭대학 의학부 이비인후과학교실) ;
- 서영표 (가톨릭대학 의학부 이비인후과학교실) ;
-
김민식
(가톨릭대학 의학부 이비인후과학교실)
;
- 조승호 (가톨릭대학 의학부 이비인후과학교실) ;
- 서병도 (가톨릭대학 의학부 이비인후과학교실)
- Published : 1991.12.01
Abstract
Malignant oncocytoma(oxyphil cell adenoma) is a extremely rare malignant tumor of the salivary glands and almost occurs in the parotid gland. A case of malignant oncocytoma of the parotid gland occurring in a 63 year old man is reported. Establishing a diagnosis of malignant oncocytoma essentially requires the application of two sets of criteria to the tumor under examination. First, the tumor cells must be identified as oncocyte and second, malignancy must be determined. Histochemical stains are not as useful as generally believed. Electron microscopy confirms the diagnosis by demonstrating an abundance of mitochondria. The diagnosis of malignant oncocytoma depends on several additional criteria in addition to cellular and nuclear pleomorphism, including lack of encapsulation, local infiltration, perineural and intravascular growth, and regional and/or distant metastasis. Satisfactory results from surgical resection and postoperative radiotherapy in our patient serve as additional experience in the treatment of this rare malignancy.