Restorative Dentistry and Endodontics
- Volume 16 Issue 1
- /
- Pages.226-235
- /
- 1991
- /
- 2234-7658(pISSN)
- /
- 2234-7666(eISSN)
ANTIMICROBIAL EFFECT OF MINOCYCLINE EMBEDDED IN POLYCAPROLACTONE ON NECROTIC CANAL
괴사치수 근관에서 항생제 국소약물송달제제의 항균효과에 관한 연구
- Kwon, Soo-Kyoung (Department of Conservative Dentistry, College of Dentistry, Seoul National University) ;
- Yoom, Soo-Han (Department of Conservative Dentistry, College of Dentistry, Seoul National University)
- Published : 1991.03.25
Abstract
Therapeutic use of antibiotics in the pulpal disease should reduce the clinical symptoms and pathogenic microflora in the pulp. The purpose of this study was focused on local drug delivery into the root canal in endodontic therapy. Monolithic films from polycaprolactone and polyethylene glycol preparations with minocycline were prepared, and then the antimicrobial effect of these films on necrotic canal was tested. A total 17 necrotized pulp teeth were sampled before and 1 week after insertion of film into the pulp. Bacterial culture were performed with anaerobical condition and seeded in the 5 selective and non - selective media for 7 days in
Keywords