Journal of Preventive Medicine and Public Health
- 제24권3호
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- Pages.287-304
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- 1991
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- 1975-8375(pISSN)
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- 2233-4521(eISSN)
Cadmium에 의한 흰쥐의 간장 및 신장의 Metallothionein 변화와 방어효과
Metallothionein Induction and Its Protective Effect in Liver and Kidney of Rats Exposed to Cadmium Chloride
- 김남송 (전북대학교 의과대학 예방의학교실) ;
- 이재형 (전북대학교 의과대학 예방의학교실) ;
- 고대하 (전북대학교 의과대학 예방의학교실) ;
- 기노석 (전북대학교 의과대학 예방의학교실) ;
- 황인담 (원광대학교 의과대학 예방의학교실)
- Kim, Nam-Song (Department of Preventive Medicine and Public Health, College of Medicine, Chonbuk National University) ;
- Lee, Jae-Hyung (Department of Preventive Medicine and Public Health, College of Medicine, Chonbuk National University) ;
- Koh, Dai-Ha (Department of Preventive Medicine and Public Health, College of Medicine, Chonbuk National University) ;
- Ki, No-Suk (Department of Preventive Medicine and Public Health, College of Medicine, Chonbuk National University) ;
- Hwang, In-Dam (Department of Preventive Medicine and Public Health, College of Medicine, Won-Kwang University)
- 발행 : 1991.09.01
초록
Tolerance to several toxic effects of cadmium, including lethality has been shown following pretreatment with cadmium and zinc. This study was designed to determine if tolerance also develops to Cd-induced hepatotoxicityandrenaltoxicity. Three groups of rats (A, B, C), each consisting of 16 rats, were studied and each group was divided into four subgroups (1, 2, 3, 4), 4 rats for each subgroup. Rats were subcutaneously pretreated with saline (A),