Journal of Yeungnam Medical Science
- Volume 8 Issue 2
- /
- Pages.209-216
- /
- 1991
- /
- 2799-8010(eISSN)
Acute Megakaryoblastic Leukemia
급성 거핵아구성 백혈병 1례
- Kim, Young-Jin (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
-
Kim, Tae-Nyun
(Department of Internal Medicine, College of Medicine, Yeungnam University)
;
- Hyun, Myung-Soo (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Shim, Bong-Sup (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Lee, Hyun-Woo (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Kim, Jung-Suk (Department of Clinical Pathology, College of Medicine, Yeungnam University)
- 김영진 (영남대학교 의과대학 내과학교실) ;
-
김태년
(영남대학교 의과대학 내과학교실)
;
- 현명수 (영남대학교 의과대학 내과학교실) ;
- 심봉섭 (영남대학교 의과대학 내과학교실) ;
- 이현우 (영남대학교 의과대학 내과학교실) ;
- 김정숙 (영남대학교 의과대학 임상병리학교실)
- Published : 1991.12.30
Abstract
Acute Megakaryoblastic leukemia is a rare and rapidly fatal disease characterized by proliferation of megakaryocyte series and atypical megakaryocytes in the bone marrow. Acute Megakaryoblastic leukemia is suspicious when 1) megakaryocyte in peripheral blood, mixture of large and small mononuclear megakaryoblast in the bone marrow 2) cytoplasmic budding in blast 3) myelofibrosis (dense medullary overgrowth of reticulin fibers) 4) PAS(+), ANAE(+), SBB(-), peroxidase(-) and which is confirmed by platelet peroxidase oxidation on electromicroscope or monoclonal antibody. A case of aute megakaryoblastic leukemia was studied morphologically and monoclonal antibody.