Effect of Enrofloxacin on Post Weaning Diarrhea in Pig

돼지의 이유자돈 설사증에 대한 Enrofloxacin의 효과

For the purpose of effective therapy and prevention of post weaning E. coli diarrhea, Enrofloxacin-(Baytril premix) was administered in the feed and a series of investigations were made the occurence of diarrhea, weight gain, feed conversion rate, changes In the counts of faecal E. coli and susceptibility of the isolated E. coli strains to antimicrobials. The results obtained were as follows 1. The weaned piglets which were treated with Baytril premix gained the average body weight of 3.2kg over the control group at the age of 62 days. The result indicates a marked weight gain effect which, by statiscal analysis, showed a significant difference(P<0.01). Administration of Baytril premix also resulted in the improvement of feed conversion rate and provention of post weaning diarrhea. 2. The counts of faecal E. coli in Baytri premx treated piglets showed a marked decrease from 3.14${\times}$10$\^$8/cells/g to 2${\times}$10$\^$7/cells/g at 5days post treatment and 1${\times}$10$\^$5/cells/g at 10 days post treatment. 3. 10 strains of E. coli isolated fred the experimental pig farm were highly susceptible to Bayoil, gentamicin and trimethoprim plus sulfamethoxazole.

돼지의 이유자돈 설사병을 효과적으로 치료, 예방하고자 Enrofloxacin(Baytril premix)을 사료에 혼합투여하여 설사 발생여부, 증체량, 사료요구율, 돈분내 대장균수의 변화, 분리한 대장균의 항균물질에 대한 감수성을 조사하여 다음과 같은 결과를 얻었다. 1. 이유자돈에 Baytril premix를 급여하였던 바 대조구보다 62일령에서 체중은 3.2kg의 통계적 유의차이를 보여(p<0.01) 현저한 증체효과 나타내었으며, 사료요구율도 계선되었고 설사발생도 예방할 수 있었다. 2. Baytril Premix를 급여한 자돈의 분변내 대장균수는 3.14$\times$$10^{8}$에서 5일후 2$\times$$10^{7}$ 개/g 10일후 1$\times$$10^{5}$개/g으로 현저히 감소하였다. 3. 공시농장에서 분리한 E. coli 10중의 항균물질에 대한 감수성은 baytril, gentamicin 및 trimeoprim＋sulfamethoxazole에 감수성이 우수하였다.다.