한국환경보건학회지 (Journal of Environmental Health Sciences)
- 제17권1호
- /
- Pages.104-109
- /
- 1991
- /
- 1738-4087(pISSN)
- /
- 2233-8616(eISSN)
Carbamate 화합물의 합성 및 보건학적 연구
Synthesis and Biological Activities of Carbamate Derivative
초록
Carbamates are generally used as insecticide, thus 8-hydroxy-5-chloroquinolinyl-N-ethylcarbamate was newly synthesized. Its physical properties were determined and chemical structure was identified by means of IR, nmr in addition to elemental analysis. The effect of the compound on rat's ileum, and antibacterial activity against Staphylococcus aureus, Salmonella typhi, E. coli, and Pseudomonas aeruginosa were examined. It was observed that the dosage over 100 $\mu$g/ml of the compound relaxed rat's ileum and the same dosage of the compound inhibited growth of the above strains of bacteria.
키워드