Toxicological Research

  • 제7권2호
  • /
  • Pages.173-181
  • /
  • 1991
  • /
  • 1976-8257(pISSN)
  • /
  • 2234-2753(eISSN)
한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

A STUDY ON MEMBRANE TRANSPORT OF BRAZILIN USING PRIMARY CULTURED RAT HEPATOCYTES

  • 발행 : 1991.12.01
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초록

Membrane transport of brazilin was investigated i primary cultured rat hepatocytes. Brazilin was transported into hepatocytes very slowly and reached plateau at about 60 minutes. Saturation of transport process was not observed and the transport was not affected by ouabain, metabolic inhibitors, and its structural analog. The amount of brazilin transported into hepatocytes was decreased when the environmental temperature was decreased. These results suggest that brazilin might be transported into hepatocytes by simple diffusional process.

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참고문헌

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