ASSAY OF POTENTIAL ANTIMUTAGENICITY OF ETHNIC MEDICINAL PLANT EXTRACTS OF PAPUA NEW GUINEA BY USING SOS CHROMOTEST (E. coLi PQ 37)

  • K. Sundarrao (Department of Chemistry University of Puppua New Guinea) ;
  • Jeho Yum (Department of Chemistry University of Puppua New Guinea) ;
  • Chang, Il-Moo (Department of Chemistry University of Puppua New Guinea)
  • 발행 : 1991.12.01

초록

Thirty six crude drug samples have been prepared from different parts of twenty five plants belonging to different families, and antimutangenic activities were studied by using SOS chromotest (E. coli PQ 37). The following crude extracts of PNG medicinal plants which had a appreciable antimutagenic activity against mitomycin C were: Artocarpus communis (stem bark), Cycas circinalis (leaves), Merremia peltata (leaves), Intsia palembanica (leaves), Annona muricata (stem bark), and Artocarpus altilis (root bark).

키워드

참고문헌

  1. Korean J. Pharmacog. v.12 Toxoicity and antitumor activities of Korean Medicinal Plants (1) Chang,I.M.;Chi,H.J.
  2. Korean J. Pharmacog. v.13 Toxicological evaluation of medicinal plants used for herbal drugs (Ⅱ); Acute toxicity and effects on DNA biosynthesis on bone marrow cells and hemoglobin content in blood Chang,I.M.;Kim,Y.S.;Han,B.H.
  3. Korean J. Pharmacog. v.13 Toxicological evaluation of medicinal plants used for herbal drugs (Ⅳ), acute toxicity and antitumor activities Chang,I.M.;Kim,J.H.;Han,D.S.
  4. Korean J. Pharmacog. v.13 Toxicological evaluation of medicinal plants used for herbal drugs (Ⅲ): cytotoxicity and antitumor activities against Glioma (9ASK) Chang,I.M.;Chi,H.J.
  5. Proceeding of the first Korea-Japan Toxicology Symposium Safety Assessment of Chemicals In Vitro Assay of potential mutagenicity and antimutagenicity of Chinese herbal drugs by using SOS chromotest (E. Coli PQ37) and SOS UMU test (S. Typhimurium TA 1535/PSK 1002) Chang,I.M.;Guest,I.C.;Lee-Chang,J.;Paik,N.W.;Jhoun,J.;Ryun,R.Y.
  6. Agr. Biol. Chem. v.48 Antimutagenic diterpenoids from a crude drug Isodonis herba (Enmei-SO) Kakinuma,K.;Okada,Y.;Ikegawa,N.;Kada,T.;Nomoto,M.
  7. Agric. Biol. Chem. v.48 Cinnamaldehyde: Identification of an antimutagen from a crude drug, Cinnamomi cortex Kakinuma,K.;Koike,J.;Kotani,J.;Ikegawa,N.;Kada,T.;Nomoto,M.
  8. Korean J. Toxicol. v.2 Toxicological study on traditional Korean herbal drugs (Ⅴ) Kalantary Gotvandi,H.N.;Zong,M.;Chang,I.M.
  9. Mutation Res. v.116 Protoanemonin, an antimutagen isolated from plants Minakata,H.;Komura,H.;Nakanishi,K.;Kada,T.
  10. Zingiber officinale. Mutation Res. v.103 Mutagen and antimutagen in ginger Nakamura,H.;Yamamoto,T.
  11. A review J. Natural Products v.53 Annonaceous acetogenins Rupprecht,J.K.;Hui,Y.H.;McLaughlin,J.L.
  12. Mutation Res. v.174 Antimutagenecity of extracts from crude drugs in Chinese medicines Sakai,Y.;Nagase,H.;Ose,Y.;Sato,Y.;Yamada,A.;Hibi,M.;Yamada,F.
  13. Advanced in Chinese Medicinal Materials Research Toxicity and side effects of some hinese medicinal herbs Wang,Y.M.;Hu,Y.J.;Chang,H.M.;Yeung,H.W.;Tso,W.W.;Koo,A.(ed.)