Toxicological Research

  • 제7권1호
  • /
  • Pages.51-59
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  • 1991
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  • 1976-8257(pISSN)
  • /
  • 2234-2753(eISSN)
한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

랫트에 있어서 절수, 절식 및 절수 절식이 혈액학 및 혈액생화학적 PARAMETERS에 미치는 영향에 관한 연구

  • 한상섭 (한국화학연구소 안정성연구센터) ;
  • 송창우 (한국화학연구소 안정성연구센터) ;
  • 이치호 (한국화학연구소 안정성연구센터)
  • 발행 : 1991.06.01
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초록

The purpose of the present study was to investigate the effects of non-watering, fasting and non-watering fasting for 16-17 hrs on haematological and biochemical parameters in SD rats. 1. Liver weight was decreased in the order of in the fasting group, non-watering fasting group and non-watering group in both sexes. 2. In fasting group and non-watering fasting group, haematologic parameters of male (HGB and MCH) and femal (MCHC) were trends to decrease compared with normal feeding & watering group. 3. In the differential leucocyte counts, there were no significant differences compared with noraml feeding % watering group.

키워드

참고문헌

  1. Laboratory Animal Science v.26 Effect of Overnight Fasting of Young Rats on Water Consumption, Body Weight, Blood Sampling, and Blood Composition Alex Apostolou(et al.)
  2. Laboratory Animals v.15 The Effect of Fasting on Oral Acute Toxicity of Drugs in Rats and Mice Alexander Kast(et al.)
  3. Exp. Animal v.25 no.3 Clinico-Biochemical Data on Laboratory Animals-A Review Nagase;Sumi
  4. Principles and Methods of Toxicology Wallace,A.;Hayes
  5. Fundamental and applied Toxicol. v.8 Age-Related Changes in Serum Chemistry and Haematology Values in Normal Sprague-Dawley Rats Wolford,S.T.
  6. J. of Toxicol. and Environ. Health v.18 Reference Range Data Base for Serumchemistry and Haematology Values Laboratory Animals Wolford,S.T.
  7. Biochemistry of Blood and Urine in Experimental Animals Yamamoto