Synthesis of 2,3-Alkyl Substituted Aziridinecarboximidates and Their in vitro Cytotoxicity

2,3-Alkyl Aziridinecarboximidate류의 합성 및 항암효과 평가

Seven drivatives of 2, 3-alkyl substituted aziridinecarboximidates were prepared from alkyl substituted alkene and cyanamide. Their ED$_{50}$ values against L$_{1210}$ cell in vitro were evaluated as 1.5 to 4 $\mu\textrm{g}$/ml.