YAKHAK HOEJI (약학회지)
- Volume 35 Issue 3
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- Pages.203-215
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- 1991
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Augmentation of the Cytotoxic Effects of Anticancer Drugs by $(\pm)$ -ar-Turmerone and Extracts of the Lithosperma and Scutellaria Roots against Human Leukemia Cell Lines
백혈병 세포주에 대한 $(\pm)$ -ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과
Abstract
Using the calorimetric [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT)assay, we evaluated the chemosensitivity of 8 anticancer drugs{vincristine(VCR), vinblastine(VBL), adriamycin(ADR), cisplatin(CPDD), etoposide(VP-16), cytosine arabinoside(ara-C), bleomycin (Bleo) and cyclophosphamide(CYC)} and the cytotoxicity-enhancing effects of (
Keywords
- Chemosensitivity;
- anticancer drugs;
- cytotoxicity-enhancing effects;
- $(\pm)$-ar-turmerone;
- Lithosperma;
- Scutellaria roots