YAKHAK HOEJI (약학회지)
- Volume 35 Issue 3
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- Pages.190-196
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- 1991
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Regiospecific N-, N'-Monoalkylation of Ditertiary Diamine Compounds
Ditertiary Diamine 화합물의 Regiospecific N-, N'-Monoalkyl화 반응
Abstract
N-monoalkyiations of ditertiary diamines succeed best in nitromethane or ethanol at low temperature, unsymmetrical piperazine and piperidine compounds react selectively under these condition at the sterically less hindered nitrogen atom.