Regiospecific N-, N'-Monoalkylation of Ditertiary Diamine Compounds

Ditertiary Diamine 화합물의 Regiospecific N-, N'-Monoalkyl화 반응

N-monoalkyiations of ditertiary diamines succeed best in nitromethane or ethanol at low temperature, unsymmetrical piperazine and piperidine compounds react selectively under these condition at the sterically less hindered nitrogen atom.