생약학회지 (Korean Journal of Pharmacognosy)
- 제22권3호
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- Pages.192-196
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- 1991
- /
- 0253-3073(pISSN)
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- 2288-9299(eISSN)
황금의 Bradykinin 길항작용
Bradykinin Antagonistic Activities of Scutellariae Radix
-
Chung, Sung-Hyun
(College of Pharmacy, Kyunghee University)
;
- Choi, Jin-Jae (College of Pharmacy, Kyunghee University) ;
- Yoo, Kyung-Sook (Natural Products Research Institute, Seoul National University) ;
-
Yun-Choi, Hye-Sook
(Natural Products Research Institute, Seoul National University)
- 발행 : 1991.09.30
초록
Ether-soluble flavonoid and neutral fraction (Fr. C) prepared from EtOAc extract of Scutellariae Radix showed inhibitory activities against bradykinin (BK) ; inhibited BK-induced ileum or uterus contractions, antagonized BK-induced plasma extravasation and protected mice from endotoxic shock, reduced acetic acid-induced writhing in mice.