Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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Prediction of Endogenous LH Surge and its Effects on Outcome of IVF in Controlled Ovarian Hyperstimulation

체외수정시술시 내인성 LH Surge의 예측과 체외수정의 결과에 미치는 영향에 관한 연구

  • Cho, Hae-Sung (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Lee, Kee-Soon (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Kim, Soo-Won (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Baik, Cheong-Soon (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Cho, Kyung-Sook (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Kim, Jae-Myeoung (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Suh, Byung-Hee (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic) ;
  • Lee, Jae-Hyun (Department of Obstetrics and Gynecology, college of medicine, Kyung Hee University, Infertility Clinic)
  • 조해성 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 이기순 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 김수원 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 백청순 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 조경숙 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 김재명 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 서병희 (경희대학교 의과대학 산부인과학교실, 불임크리??) ;
  • 이재현 (경희대학교 의과대학 산부인과학교실, 불임크리??)
  • Published : 1990.11.30
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Abstract

At infertility clinic, department of Obstetrics and Gynegology, Kyung Hee Medical Hospital, 80 patients who underwent IVF-ET from January to July, 1989 were evaluated for the prediction of endogenous LH Surge and its effects on outcome of controlled ovarian hyperstimulation (COH) were compared among LH Surge group without hCG given (N=18), with hCG given (N=5), and no-LH Surge group with hCG given (N=57). LH Surge were occurred in 23(28.7%) out of 80 patients studied. Serum E2 levels on Day-1, Day 0, Day+1, were no significant different among three groups. When basal serum LH/FSH ratio is above 1.0, the possibility of endogenous LH Surge is much higher (56.3% in LH Surge group without hCG given). Serum P4 levels on Day 0 were significantly increased in LH Surge group without hCG given. Cycles which serum P4 level is higher than l.0ng/ml were 70.6% of LH Surge group without hCG given. But there was no significant interrelationship between endogenous LH Surge and serum P4 rising rate as an efficient predictor of the occurrence of endogenous LH Surge in COH for IVF. There was no significant differences in number of follicles, follicular size on Day-1, Day 0, Day+1, and number of oocyte collected per cycle. The oocyte fertilization rate of No-LH surge group with hCG given was significantly higher than LH Surge group without hCG given. There was no significant difference in oocyte cleavage rate among three groups.

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