두경부암의 방사선치료에서 치료실패의 요인에 관한 분석 - 임상 및 방사선 생물학적 측면에서의 고찰 -

Causes of Failure in the Radiation Therapy of Head and Neck Cancer - Clinico-Radiobiogical Correlations-

This review will be discussed the various causes of radiation failure for head and neck cancers from radiobiologic perspective and also provided a few clinical data to illustrate the basic principle. A knowledge about multiplicity of factors that may underlie failure of radiation treatment is essential for rational application of new treatment strategies. Furthermore, it is important to distinguish causes of failure that can be reduced or minimized by application of conventional treatment from one are potentially remediable by new treatment strategies, and one that are not amenable to some modification of radiotherapeutic approach.