Investigation of the Reaction of 6-Amino-3-methyl-4-oxo-3, 4-dihydro-2-pyrimidinylhydrazine

  • Moustafa, M.A. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • Gineinah, M.M. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • Bayomi, S.M. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • Ismaiel, A.M. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura)
  • Published : 1990.12.01

Abstract

The hydrazine derivative 2 has been utilized for the synthesis of three different fused 1, 2, 4-triazolo [4, 3-a] pyrimidine derivatives 4, 5, &6 and a tetrazolo [1, 5-a] pyrimidine derivative 7. Reaction of 2 with the chalcone analogue 2-thenylidene-2'-acetothienone, gave the pyrazoline derivative 8.

Keywords