Reactions with Hydrazidoyl Halides (V): Synthesis of Some Amidrazones, Hydrazides, Pyrazoles and Pyrazolo [3, 4-d] pyridazine Derivatives

  • Attaby, Fawzy A. (Department of Chemistry, Faculty of Science, Cairo University) ;
  • Zaki, Mayssoune Y. (Department of Chemistry, Faculty of Science, Cairo University) ;
  • Abdelhamid, Abdou O. (Department of Chemistry, Faculty of Science, Cairo University) ;
  • Ramadan, Nazmy A. (Petroleum Research Institute)
  • Published : 1990.12.01

Abstract

2-Bromo (2'-benzofury)gloxal-2-aryhydrazones I reacted with nucleophiles displacing the bromide. Treatment of I with active methylene compounds yield the pyrazole derivatives VIII-XI. Compounds XII-XIV reacted with hydrazine to give pyrazolo (3, 4-dipyridazine derivative XIV-XIV. The structures of the products were assigned and confirmed on the basis of their elemental analysis and spectral data.

Keywords