Archives of Pharmacal Research
- Volume 13 Issue 4
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- Pages.314-318
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- 1990
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Reactions with Hydrazidoyl Halides (V): Synthesis of Some Amidrazones, Hydrazides, Pyrazoles and Pyrazolo [3, 4-d] pyridazine Derivatives
- Attaby, Fawzy A. (Department of Chemistry, Faculty of Science, Cairo University) ;
- Zaki, Mayssoune Y. (Department of Chemistry, Faculty of Science, Cairo University) ;
- Abdelhamid, Abdou O. (Department of Chemistry, Faculty of Science, Cairo University) ;
- Ramadan, Nazmy A. (Petroleum Research Institute)
- Published : 1990.12.01
Abstract
2-Bromo (2'-benzofury)gloxal-2-aryhydrazones I reacted with nucleophiles displacing the bromide. Treatment of I with active methylene compounds yield the pyrazole derivatives VIII-XI. Compounds XII-XIV reacted with hydrazine to give pyrazolo (3, 4-dipyridazine derivative XIV-XIV. The structures of the products were assigned and confirmed on the basis of their elemental analysis and spectral data.