Archives of Pharmacal Research
- Volume 13 Issue 2
- /
- Pages.201-203
- /
- 1990
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Synthesis of cis-disubstitude cyclohexane synthesis of cis-1-ethenyl-2-hydroxymethyl-cyclohexane
-
Suh, Young-Ger
(College of Pharmacy, Seoul National University)
;
- Kim, Soon-Ai (College of Pharmacy, Seoul National University) ;
- Cho, Youn-Sang (College of Pharmacy, Seoul National University)
- Published : 1990.06.01
Abstract
The efficient synthetic routes to cis-1-ethenyl-2-hydroxymethyl-cyclohexane, an useful synthetic intermediate, have been described. Access to the cis-disubstituted cyclo hexane is gained through the Clasen rearrangment and selective DHP protection of diol respectively.
Keywords
- cis-l-ethenyl-2-hydroxymethyl-cyclohexane;
- Claisen rearrangement;
- iodohexanoic acid;
- selective DHP protection of diol