Archives of Pharmacal Research
- Volume 13 Issue 2
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- Pages.187-191
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- 1990
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of Some Heterocycles of Potential Biological Activity
- Ali-Harb, Abd-Elfattah (Faculty of Science, Qena, Assiut University) ;
- Mostafa, Fatma-H. (Faculty of Science, Qena, Assiut University) ;
- Metwally, Saoud-A. (Faculty of Science, Assiut, Assiut University)
- Published : 1990.06.01
Abstract
A convenient method for the preparation of imidazobenzimidazole 3, imidazoimidazole 5, imidazotriazole 6 and pyrano [2, 3-c] oxazole 7 derivatives is described. This depends on interaction of 2-methyl-4-arylidene-2-oxazolin-5-ones 1 with o-diamines, thiosemicarbazide and/or ethylcyanoacetate. The effect of alcoholic potassium cyanide on axazolinone 1 was studied. Antibacterial activity of the obtained products was studied.
Keywords
- Imidazobenzimidazole;
- imidazoimdazole;
- benzothiazole;
- imidazotriazole;
- pyranooxyzole;
- antibacterials activity