Applied Biological Chemistry
- Volume 33 Issue 3
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- Pages.264-267
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- 1990
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- 2468-0834(pISSN)
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- 2468-0842(eISSN)
Fungicidal activity of synthetic piericidin analogs as inhibitors of NADH-ubiquinone oxidoreductase on the respiratory chain
호습쇄의 NADH-ubiquinone oxidoreductase 저해제인 합성 piericidin유사체드르이 살균활성
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Chung, Kun-Hoe
(Organic Div. I, Korea Research Institute of Chemical Technology (KRICT)) ;
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Cho, Kwang-Yun
(Organic Div. I, Korea Research Institute of Chemical Technology (KRICT)) ;
- Takahashi, Nobutaka (Department of Agricultural Chemistry, The University of Tokyo) ;
- Yoshida, Shigeo (Chemical Regulation of Biomechanisms Lab., The Institute of Chemical and Physical Research (RIKEN))
- Published : 1990.09.30
Abstract
Representative synthetic piericidin-like compounds, such as hydroxypyridine and hydroxyquinoline derivatives, which showed high inhibition activity against NADH-ubiquinone oxidoreductase on the respiratory chain revealed good fungicide activity. Especially, hydrolrypyridine ones showed high activity against rice blast (Pyricularia oryzae) and barley powdery mildew (Erysiphe graminis).
호습쇄의 NADH-ubiquinone oxidoreductase를 강력히 저해하는 합성 piericidin유사체로써 hydroxypyridine 및 hyoxyquinoline 유도체들이 전반적으로 좋은 살균활성을 보였다. 특히, hydroxypyfidine 유도체들은 벼도열병(Pyricularia oryzae)과 보리흰가루병(Erysiphe graminis)에 대해서 높은 살균활성을 나타했다.
Keywords
- NADH-ubiquinone oxidoreductase;
- respiratory chain;
- inhibitor;
- piericidin;
- ubiquinone;
- hydroxypyridine;
- hydroxyquinoloine;
- respiratory electron transport;
- (sub)mitochondria