생약학회지 (Korean Journal of Pharmacognosy)
- 제21권2호
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- Pages.130-136
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- 1990
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
한국산(韓國産) 복수초성분(福壽草成分)의 $Na^+,\;K^+-ATPase$ 활성(活性)에 대한 연구(硏究)
Studies on $Na^+,\;K^+-ATPase$ Activity of the Constituents of Adonis amurensis in Korea
- 노재섭 (충북대학교 약학대학) ;
- 이경순 (충북대학교 약학대학) ;
- 박웅양 (충북대학교 약학대학) ;
- 오갑진 (충북대학교 약학대학) ;
- 안병태 (충북대학교 약학대학) ;
- 어경춘 (충북대학교 약학대학) ;
- 정도래 (충북대학교 약학대학) ;
- Ro, Jai-Seup (College of Pharmacy, Chungbuk National University) ;
- Lee, Kyong-Soon (College of Pharmacy, Chungbuk National University) ;
- Park, Woong-Yang (College of Pharmacy, Chungbuk National University) ;
- Oh, Kap-Jin (College of Pharmacy, Chungbuk National University) ;
- Ahn, Beung-Tae (College of Pharmacy, Chungbuk National University) ;
- Eo, Kyong-Chun (College of Pharmacy, Chungbuk National University) ;
- Jeong, Do-Rae (College of Pharmacy, Chungbuk National University) ;
- Nambara, Toshio (Pharmaceutical Institute, Tohoku University)
- 발행 : 1990.06.30
초록
Four known cardiotonic steroids were isolated from roots of Adonis amurensis Regel et Radde and identified as digitoxigenin, cymarin, K-strophanthin and convallatoxin by chromatography on Amberlite XAD-2 resin and silica gel, high performance liquid chromatography and gel chromatography on Sephadex LH-20. In order to clarify the structure-activity relationship, thirteen related compounds of digitoxigenin were tested for the inhibitory activities for
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