Korean Journal of Pharmacognosy (생약학회지)
- Volume 21 Issue 2
- /
- Pages.130-136
- /
- 1990
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Studies on $Na^+,\;K^+-ATPase$ Activity of the Constituents of Adonis amurensis in Korea
한국산(韓國産) 복수초성분(福壽草成分)의 $Na^+,\;K^+-ATPase$ 활성(活性)에 대한 연구(硏究)
-
Ro, Jai-Seup
(College of Pharmacy, Chungbuk National University)
;
-
Lee, Kyong-Soon
(College of Pharmacy, Chungbuk National University)
;
- Park, Woong-Yang (College of Pharmacy, Chungbuk National University) ;
- Oh, Kap-Jin (College of Pharmacy, Chungbuk National University) ;
- Ahn, Beung-Tae (College of Pharmacy, Chungbuk National University) ;
- Eo, Kyong-Chun (College of Pharmacy, Chungbuk National University) ;
- Jeong, Do-Rae (College of Pharmacy, Chungbuk National University) ;
- Nambara, Toshio (Pharmaceutical Institute, Tohoku University)
-
노재섭
(충북대학교 약학대학)
;
-
이경순
(충북대학교 약학대학)
;
- 박웅양 (충북대학교 약학대학) ;
- 오갑진 (충북대학교 약학대학) ;
- 안병태 (충북대학교 약학대학) ;
- 어경춘 (충북대학교 약학대학) ;
- 정도래 (충북대학교 약학대학) ;
- Published : 1990.06.30
Abstract
Four known cardiotonic steroids were isolated from roots of Adonis amurensis Regel et Radde and identified as digitoxigenin, cymarin, K-strophanthin and convallatoxin by chromatography on Amberlite XAD-2 resin and silica gel, high performance liquid chromatography and gel chromatography on Sephadex LH-20. In order to clarify the structure-activity relationship, thirteen related compounds of digitoxigenin were tested for the inhibitory activities for
Keywords
- Adonis amurensis;
- $Na^+,\;
- K^+-ATPase$;
- structure-activity, relationship;
- digitoxigenin;
- cymarin;
- K-strophanthin;
- convallatoxin