The Korean Journal of Mycology (한국균학회지)
- Volume 18 Issue 1
- /
- Pages.13-19
- /
- 1990
- /
- 0253-651X(pISSN)
- /
- 2383-5249(eISSN)
Production of T-2 Toxin and Its Metabolites by Fusarium sporotrichioides Isolates from the Corn Producing Area in Korea
우리나라 옥수수산지에서 분리한 Fusarium sporotrichioides 균주들에 의한 T-2 독소 및 관련 대사물의 생성
-
Lee, Yin-Won
(Department of Agricultural Biology, College of Agriculture, Seoul National University) ;
-
Kim, Kook-Hyung
(Department of Agricultural Biology, College of Agriculture, Seoul National University) ;
- Chung, Hoo-Sup (Department of Agricultural Biology, College of Agriculture, Seoul National University)
- Published : 1990.03.30
Abstract
Four isolates of Fusarium sporotrichioides obtained from the corn producing area were tested for their toxicities by feeding the crude cultures to rats. Three out of four isolates were highly toxic and killed all rats within 3-4 days after feeding. The chemical analyses of toxic cultures by thin layer chromatography and gas chromatography-mass spectrometry revealed that two isolates from Jeongsun district produced T-2 toxin and its related trichothecenes. This is the first report that F. sporotrichioides isolates produce T-2 toxin in Korea.
우리나라 옥수수산지로부터 분리한 Fusarium sporotrichioides 4균주의 밀배양체를 쥐에 경구투여하여 독성을 조사하였다. 총 4균주 중 3균주가 급여 3-4일 이내에 모든 쥐를 치사시켜 매우 높은 독성을 나타냈다. 독성 균주의 배양체를 박층크로마토그라피와 가스크로마토그라피 - 질량분석기로 분석한 결과 정선 지방에서 분리한 2균주가 T-2 독소와 관련대사물을 생성하였다. 본 보고는 F. sporotrichioides에 의한 T-2 독소의 생성을 우리나라에서는 처음으로 확인한 것이다.