YAKHAK HOEJI (약학회지)
- Volume 34 Issue 3
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- Pages.192-198
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- 1990
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
The Effect on the Dissolution Rate of Sulfamerazine from Sugar Glass Dispersion System
Sulfamerazine-Sugar Glass Dispersion의 용출속도에 관한 연구
- Ku, Young-Soon (College of Pharmacy, Ewha Woman's University) ;
- Sung, Kyung-Soo (College of Pharmacy, Ewha Woman's University)
- Published : 1990.06.28
Abstract
Three sugar glass dispersions of sulfamerazine were prepared using dextrose, galactose and sucrose as the carriers, with the ratio of the drug to the carrier was 1:9. The chemical stability of sulfamerazine in the glass dispersion system was studied using TLC. TLC revealed no additional spot and there was good correspondence with the Sulfamerazine itself. While time required to dissolve 50%(