Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
권호 표지

AN EXPERIMENTAL STUDY ON THE CYTOTOXICITY OF SEVERAL COMPOSITE RESINS

수종(數種) 치과(齒科) 수복용(修復用) 복합(複合)레진의 세포독성(細胞毒性)에 관(關)한 실험적(實驗的) 연구(硏究)

  • Myoung, Jae-Keun (Department of Operative Dentistry, College of Dentistry, Seoul National University) ;
  • Lee, Myoung-Jong (Department of Operative Dentistry, College of Dentistry, Seoul National University)
  • 명제근 (서울대학교 치과대학 치과보존학교실) ;
  • 이명종 (서울대학교 치과대학 치과보존학교실)
  • Published : 1989.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

This study was conducted to evaluate the influence of 5 microfilled composite resin to fibroblast cultivated from human pulp (age 13). Each composite resin was manually mixed and filled in cylinder. Resin filled cylinders were placed in dishes (35mm in diameter) containing 3 ml of ${\alpha}$-MEM. Filters (pore size 0.22 ${\mu}m$) to simulate dentin were also placed between the bottom of cylinder and the dish floor. Then stored in 5% $CO_2$ containing incubator for 1 and 2 weeks at the temperature 36.6 C. The results analysed after 1 and 2 weeks were as follows: 1. Experimental group except group 2, 2 weeks incubation cases showed the cytotoxicity compared to the control group in cell count. 2. After 2 week-incubation of group 1 and group 4, cell count was more decreased than 1 week cases and cytotoxicity seemed to be constantly influenced to the cell multiplication. 3. The cell growth rate of 1 week incubation in group 3 and group 5 was similar to the control group and recognized the cytotoxicities of these groups were mild. 4. The cell multiplication rate of 2 week incubation cases in group 2 was greater than control group.

Keywords