한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)

  • 제6권1호
  • /
  • Pages.27-30
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  • 1989
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  • 1225-9098(pISSN)
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  • 2288-1069(eISSN)
한국응용과학기술학회 (The Korean Society of Applied Science and Technology)
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High Performance Liquid Chromatography 를 이용한 Cefatrizine ${\cdot}$ Propylene Glycol 의 분리 및 정량

Separation and Determination of Cefatrizine ${\cdot}$ Propylene Glycol by High-performance Liquid Chromatography

  • 발행 : 1989.05.31
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초록

The fast separation and determination of cefatrizine${\cdot}$propylene glycol and inmpurities - TACA: 7-amino-3-(1,2,3-triazol-4-yl)thiomethyl-3-cephem-4-carboxylic acid and 7-ACA; 7-amino cephalosporanic acid - was performed by the high poerformance liquid chromatography using octadecyl siland (ODS) column. Methanol and ammonium phosphate buffer [$0.03M(NH_4)_2\;HPO_4$, (pH 7.5)] was used analyze, as eluent. The experimental value of the contents of cefatrizine${\cdot}$propylene glycol and impurities agree with the theoretical value of those.

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