Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Polycythemia vera combined with coagulation disorder -A case report-

혈액응고 장애가 동반된 진성다혈증 1례

  • Ahn, Jae-Hee (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Lee, Du-Ha (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Chun, Hyo-Jin (Military Taegu Hospital, Department of Clinical Pathology) ;
  • Hyun, Myung-Soo (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Lee, Hyun-Woo (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Kim, Chung-Sook (Department of Clinical Pathology, College of Medicine, Yeungnam University)
  • 안재희 (영남대학교 의과대학 내과학교실) ;
  • 이두하 (영남대학교 의과대학 내과학교실) ;
  • 전효진 (국군 대구 병원 임상병리과) ;
  • 현명수 (영남대학교 의과대학 내과학교실) ;
  • 이현우 (영남대학교 의과대학 내과학교실) ;
  • 김정숙 (영남대학교 의과대학 임상병리학교실)
  • Published : 1989.12.30
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Abstract

We report a case of polycythemia vera combined with coagulation disorder. The patient was 54 years old man who complained of continuous bleeding after incision of skin abscess 20days ago. Laboratory tests were revealed prolonged aPTT and slightly prolonged PT. Coagulation factor, I, VIII, IX, XI and fibrinogen decreased, however FDP did not increased. It appears that patient with polycythemia vera have chronic activation of coagulation system, probably initiated by activation of factor XII. Platelet aggregation test to ADP, collagen, epinephrine was also revealed poor response.

피부 농양절개술 후 계속되는 출혈을 주소로 입원한 진성다혈증 환자에서 혈액응고인자, I, VIII, IX, XI등의 감소와 혈소판의 기능 장애를 동반한 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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