Xylazine과 Ketamine 병용 투여에 대한 Yohimbine의 길항 효과

Antagonism of Xylazine and Ketamine Anesthesia by Yohimbine in Goats

Antagonistic effects of yohimbine on xylazine and ketamine anesthesia in goats were studied. Xylazine or ketamine anesthesia alone was not antagonized by yohimbine, but the time for consciousness and recovery in xylazine and ketamine anesthetized goats were remarkably shortened by yohimbine. Reversal effect of yohimbine on the heart rate and body temperature which decreased following xylazine and ketamine was not observed and respiratory rate which increased after xylazine and ketamine was sligtly reduced by yohimbine.