The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Normal Control Study of Cerebral Blood Flow by Tc-99m HM-PAO SPECT

$^{99m}TC-HMPAO$ SPECT를 이용한 정상인 국소뇌혈류의 정량적 분석

  • Moon, Dae-Hyuk (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Bum-Woo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Kyung-Han (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Choi, Yoon-Ho (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Chung, June-Key (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Chul (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Yoon, Byung-Woo (Department of Neurology, College of Medicine, Seoul National University) ;
  • Lee, Nam-Soo (Department of Neurology, College of Medicine, Seoul National University) ;
  • Roh, Jae-Kyu (Department of Neurology, College of Medicine, Seoul National University) ;
  • Myung, Ho-Jin (Department of Neurology, College of Medicine, Seoul National University) ;
  • Koong, Sung-Soo (Department of Internal Medicine, College of Medicine, Chungbuk National University)
  • 문대혁 (서울대학교 의과대학 내과학교실) ;
  • 이범우 (서울대학교 의과대학 내과학교실) ;
  • 이경한 (서울대학교 의과대학 내과학교실) ;
  • 최윤호 (서울대학교 의과대학 내과학교실) ;
  • 정준기 (서울대학교 의과대학 내과학교실) ;
  • 이명철 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 윤병우 (서울대학교 의과대학 신경과학교실) ;
  • 이남수 (서울대학교 의과대학 신경과학교실) ;
  • 노재규 (서울대학교 의과대학 신경과학교실) ;
  • 명호진 (서울대학교 의과대학 신경과학교실) ;
  • 궁성수 (충북대학교 의과대학 내과학교실)
  • Published : 1989.11.13
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Abstract

Regional cerebral perfusion was evaluated in 15 normal controls by single photon emission computed tomography using $^{99m}Tc$ HM-PAO. For quantitative analysis, 13 pairs of homologous region of interest (ROI) were drawn on three transverse slices matching the vascular territories and cerebral cortices, and normal values of 3 semiqunatitative indices including 'Right to left ratio'(R/L ratio), 'Regional index'(RI), and 'Region to cerebellum ratio'(R/cbll ratio) were calculated. Mean values of R/L ratios of homotogous regions were ranged from 0.985 to 1.023, and mean ${\pm}2$ s.d. of all regions did not exceed 11% of mean. Significant difference of RIs (mean count per voxel of a ROI/mean count per voxel of total ROIs) between regions were found (p<0.001) with highest values in occipital cortex and cerebellum. After attenuation correction, RIs in deep gray, cranial portion of anterior cerebral artery and vascular territories in the 2nd slice increased significantly (p < 0.05-0.001), but vise versa in other ROIs. Region to cerebellum ratios also showed regional difference similar to RIs.

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