Isolation and Screening of Pepsin Inhibitor-Producing Actinomycetes

Pepsin 저해물질을 생산하는 방선균의 분리 및 검색

For the purpose of obtaining microorganisms which produced an extracellular pepsin inhibitor, screening test was carried out. One strain of Actinomycetes (GF 155-2) isolated from soil samples showed a high inhibitory activity against porcine pepsin. The morphological, physiological and cultural characteristics of the strain GE 155-2 on various culture media were studied according to ISP methods and Bergey's manual of determinative bacteriology (8th ed.). This Actinomycetes GE 155-2 was found to be similar to the genus Microtetraspora.

세포외로 pepsin 저해물질을 생산하는 미생물을 획득할 목적으로 screening test를 실시하여, porcine pepsin에 대하여 우수한 저해력을 나타내는 방선균 1균주(GF 155-2)를 분리하였다. 각종 배지상에서 그 형태학적·배양학적·생리학적 성질을 조사하여 본 결과 그 미생물학적 특성이 Microtetraspora속과 유사하였다.