Radiation Oncology Journal
- Volume 7 Issue 1
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- Pages.1-13
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- 1989
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
The Effect of 5-FU and Radiation on A549 Cells In Vitro
시험관내의 인체폐암 세포 A549의 방사선 및 5-Fluorouracil에 대한 효과
- Lee, Myung-Za (Department of Radiation Therapy, Hanyang University Hospital) ;
- Chun, Ha-Chong (Department of Radiation Oncalogy, Medical College of Virginia) ;
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Lee, Won-Young
(Department of Microbiology, Yonsei Medical College)
- Published : 1989.06.01
Abstract
Effects of ionizing radiation alone and combined with chemotherapy on tumor growth and it's clonal specificity monitored by changes in distribution of chromosome number were studies in A549 ceil line originated from human adenocarcinoma of the lung. Radiation (300 rad, 600 rad and 900 rad) were delivered with or without 5-FU. Forty eight hours later, 57.5% of growth inhibition of cell w8s seen in cells treated with 5-FU concentration of