Journal of Pharmaceutical Investigation
- 제19권4호
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- Pages.213-217
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- 1989
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
은행잎엑스 수용액 중 Gingkoflavonglycoside의 안정성
Stability of Gingkoflavonglycoside in Gingko Extract Aqueous Solution
-
김종국
(서울대학교 약학대학 물리약학연구실)
;
- 박만기 (서울대학교 약학대학 물리약학연구실) ;
- 이은진 (서울대학교 약학대학 물리약학연구소) ;
- 황성주 (서울대학교 약학대학 물리약학연구실)
-
Kim, Chong-Kook
(College of Pharmacy, Seoul National University)
;
- Park, Man-Ki (College of Pharmacy, Seoul National University) ;
- Lee, Eun-Jin (College of Pharmacy, Seoul National University) ;
- Hwang, Sung-Joo (College of Pharmacy, Seoul National University)
- 발행 : 1989.12.20
초록
To formulate the stable preparation of Gingko extract injection and to evaluate the stability of the preparation, Gingko extract aqueous solutions having various pH values were prepared and the stability of ginskoflavonglycoside (GFG) was investlfated by high performance liquid chromatography. The stability of GFG decreased as pH increased, while the water solubility of Gingko extract decreased as pH decreased. The optimal pH of the Gingko extract aqueous solution was found to be pH 6.5. The shelf life