Journal of Pharmaceutical Investigation
- Volume 19 Issue 1
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- Pages.21-27
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- 1989
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Oil-Water Interface Transfer of Cefoperazone Pivaloyloxymethyl Ester
세포페라존피바로일옥시메칠에스텔의 유-수 계면 이행에 관한 연구
- Choi, Young-Wook (College of Pharmacy, Chung-Ang University) ;
- Kim, Johng-Kap (College of Pharmacy, Chung-Ang University)
- Published : 1989.03.20
Abstract
Kinetic and thermodynamic aspects of the interface transfer of cefoperazone and its pivaloyloxymethyl ester were studied in a two-phase system composed of aqueous buffers and n-octanol by using the absolute reaction rate theory. In terms of the net thermodynamic parameters for the process,
Keywords
- cefoperazone;
- prodrug;
- cefoperazone pivaloyloxymethyl ester;
- interface transfer kinetics;
- thermodynamic parameters