Effect on Growth of Yeasts and Photosynthetic Bacteria by Photochemical Product of Harmaline with N-Methylmaleimide

Harmaline과 N-Methylrnaleimide의 광화학반응 생성물이 효모 및 광합성 세균의 성장에 미치는 영향

  • Ham, Heui-Suk (Department of Chemistry, College of Natural Science, Chonnam National University) ;
  • Kang, Dae-Gil (Department of Chemistry, College of Natural Science, Chonnam National University) ;
  • Choi, Won-Ki (Department of Chemistry, College of Natural Science, Chonnam National University)
  • 함희석 (전남대학교 자연과학대학 화학과) ;
  • 강대길 (전남대학교 자연과학대학 화학과) ;
  • 최원기 (전남대학교 자연과학대학 화학과)
  • Published : 1989.12.01

Abstract

The photochemical reaction of harmaline and N-methylmaleimide has been investigated by spectroscopic methods. A photoproduct was isolated from the irradiation mixture of harmaline and N-methylmaleimide. Spectroscopic results suggested that the amine group of harmaline was added photochemically to the double C=C bond of N-methylmaleimide. This synthesized harmaline derivative has a biological toxicity, because it inhibits the growth of some yeasts and photosynthetic bacteria.

N-methylmaleimide와 Harmaline의 혼합용액에서 자외선을 조사시켜 합성한 주생성물을 분광학적으로 분석하였다. 그 결과 harmaline의 아민기와 N-methylmaleimide의 탄소-탄소 이중결합 사이에 광부가 반응을 한 harmaline의 N-methylmaleimide 유도체가 얻어졌으며 이 유도체는 몇 가지의 효모 및 광합성 세균의 성장을 억제하므로 생물학적 독성을 가지고 있는 것으로 보여진다.

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