YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Localization of Transferrin mRNA in Rat by DNA/RNA Hybridization

DNA/RNA Hybridization에 의한 흰쥐의 Transferrin mRNA 분포에 관한 연구

  • Kim, Se-Eun (College of Pharmacy, Seoul National University) ;
  • Kim, Sun-Yeou (College of Pharmacy, Seoul National University) ;
  • Park, Mi-Jung (College of Pharmacy, Seoul National University) ;
  • Song, Jin-Ho (College of Pharmacy, Seoul National University) ;
  • Lee, Eun-Bang (Natural Products Research Institute, Seoul National University) ;
  • Lee, Heun-Pa (College of Pharmacy, Seoul National University) ;
  • Kim, Young-Choong (College of Pharmacy, Seoul National University)
  • Published : 1989.10.28
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Abstract

Expression of transferrin gene in various organs of rat was studied using rat transferrin cDNA. The hybridization method of $[^{35}S]-labeled$ transferrin cDNA with transferrin mRNA in cytoplasmic preparations was used to measure the level of transferrin mRNA. The rat from 15-day old fetus to 21-day old postnatal were employed as an animal model. In the liver, the level of transferrin mRNA increased with increasing age. However, the level of transferrin mRNA in brain was significantly lower than that in liver and the level did not increase with age.

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