약학회지 (YAKHAK HOEJI)
- 제33권5호
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- Pages.285-289
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- 1989
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
토복령(Smilax china)의 Steroid Saponin이 돌연변이원성에 미치는 영향
Mutagenic Effect of Steroidal Saponins from Smilax china Rhizomes
- Kim, Sung-Whan (College of Pharmacy, Yeungnam University) ;
- Son, Kun-Ho (College of Pharmacy, Yeungnam University) ;
- Chung, Kyu-Charn (College of Pharmacy, Yeungnam University)
- 발행 : 1989.10.28
초록
Pontential mutagenic and antimutagenic activities of four steroidal saponins from Smilax china rhizomes were investigated. These saponins did not revealed mutagneicity in the Ames and SOS umu test. For antimutagenic activity by SOS umu test, two spirostanol glycosides, dioscin and gracillin, inhibited the activity of