Urinary Hippuric Acid Excretion in Toluene Exposed Workers

톨루엔 폭로 근로자들의 요중 마뇨산 배설량

  • Lee, Chae-Un (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Shin, Hai-Rim (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Cho, Byung-Mann (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Moon, Deog-Hwan (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Shon, Hae-Sook (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Cho, Kyu-Il (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Kim, Sung-Chun (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College) ;
  • Kim, Yong-Wan (Department of Preventive Medicine, Institute of Industrial Medicine, Inje College)
  • 이채언 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 신해림 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 조병만 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 문덕환 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 손혜숙 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 조규일 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 김성천 (인제대학 의학부 예방의학교실 및 산업의학연구소) ;
  • 김용완 (인제대학 의학부 예방의학교실 및 산업의학연구소)
  • Published : 1988.11.01

Abstract

In order to prepare the fundamental data for preventing the hazardous effects at toluene exposure in many kinds of industry, the authors determined the level of urinary hippuric acid on 592 toluene exposed women(exposed group) and 102 unexposed women(control group) in Pusan area, from April. 1 to October 31, 1986. Hippuric acid was measured by high performance liquid chromatography. The results were summarized as follows; 1. The mean value of urinary hippuric acid concentration of the control group was $0.44{\pm}0.21g/l$(0.11-0.89g/l). The distribution of urinary hippuric acid concentration of the control group was not fit to the normal distribution. 2. The mean value of urinary hippuric acid concentration of the exposed group was $1.56{\pm}0.95g/l$(0.44-4.57g/l). The distribution of urinary hippuric acid concentration of control group was not fit to the normal distribution. 3. The urinary hippuric acid concentration by age group was not statistically significant in the control group, but in the exposed group the urinary hippuric acid concentration was highest in women between 20-29 years old($1.71{\pm}0.95g/l$) and was statistically significant(p<0.01). 4. The urinary hippuric acid concentration by duration of working hours was not statistically significant (p>0.1).

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