Applied Microscopy
- 제18권2호
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- Pages.187-204
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- 1988
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- 2287-5123(pISSN)
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- 2287-4445(eISSN)
초산납이 생쥐 간뇌의 미세구조 및 Catecholamine 대사에 미치는 영향
Acute and Subacute Effect of Lead acetate on Enzyme Activities and Ultrastructure in Mouse Diencephalone
- Lee, Jung-Hee (Dept. of Biology, Yonsei University) ;
- Yoo, Chang-Kyu (Dept. of Biology, Yonsei University) ;
- Choe, Rim-Soon (Dept. of Biology, Yonsei University)
- 발행 : 1988.12.01
초록
The present experiment was performed to investigate the acute and subacute effect of lead acetate on ultrastructural and biochemical changes in mouse diencephalon. In acute case, mouse were peritoneally injected with lead acetate at a dose of 0.26 mmole/kg body weight, and after treatment, mouse were sacrificed at time intervals of 12, 24, 48, and 96 hours. In subacute case, mouse were injected at doses of 0.07 mmoie/kg B. W. and 0.13 mmole/kg B.W. once at two days, and after treatment, mouse wee sacrificed at 1 week, 2 weeks, and 3 weeks. It was observed that after acute treatment, changes composed of increased monoamine oxidase activity,
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