치과방사선 (Journal of Korean Academy of Oral and Maxillofacial Radiology)

대한영상치의학회 (Korean Academy of Oral and Maxillofacial Radiology)
권호 표지

방사선조사가 골무기질함량에 미치는 영양에 관한 실험적 연구

AN EXPERIMENTAL STUDY ON THE CHANGE OF BONE MINERAL METABOLISM AFTER IRRADIATION

  • 진해윤 (경희대학교 치과대학 치과방사선학교실) ;
  • 이상래 (경희대학교 치과대학 치과방사선학교실)
  • Chin Hae Yun (Department of Dental Radiology, College of Dentistry, Kyung Hee University) ;
  • Lee Sang Rae (Department of Dental Radiology, College of Dentistry, Kyung Hee University)
  • 발행 : 1988.12.01
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초록

Irradiation is widely used for the treatment of malignant diseases, and possibly cause the osteoporosis. The bone densitometry and bone scintigraphy are valuable when used to monitor the patients longitudinally to access the progression of osteoporosis and risk of osteoradionecrosis. To evaluate the osteoporosis after irradiation of cobalt-60 gamma ray on the lumbar spines of New Zealand white rabbits, bone densitometry by dual photon absortiometry and bone scintigraphy were performed weekly. The decrease of bone density began at the first week after irradiation, and were in the nadir at 4-6th week. The osteoblastic activity measured by bone scintigraphy decreased in the first week, and was in the nadir at 4-6th week. The severity of these changes were related to the radiation dose. In conclusion, the osteoporosis before presentation of the osteoradionecrosis can be developed at low dose irradiation and confirmed by bone densitometry, bone scanning, and histopathology.

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